Jorge Ponseti et al. (2012)
Archives of general psychiatry
Medio: Artículo

Cita bibliográfica completa: Jorge Ponseti, Oliver Granert, Olav Jansen, Stephan Wolff, Klaus Beier, Janina Neutze, Günther Deuschl, Hubertus Mehdorn, Hartwig Siebner, Hartmut Bosinski (2012). Assessment of pedophilia using hemodynamic brain response to sexual stimuli. Archives of general psychiatry 02/2012; 69(2):187-94. ·

ABSTRACT: Accurately assessing sexual preference is important in the treatment of child sex offenders. Phallometry is the standard method to identify sexual preference; however, this measure has been criticized for its intrusiveness and limited reliability.

To evaluate whether spatial response pattern to sexual stimuli as revealed by a change in the blood oxygen level-dependent signal facilitates the identification of pedophiles.

During functional magnetic resonance imaging, pedophilic and nonpedophilic participants were briefly exposed to same- and opposite-sex images of nude children and adults. We calculated differences in blood oxygen level-dependent signals to child and adult sexual stimuli for each participant. The corresponding contrast images were entered into a group analysis to calculate whole-brain difference maps between groups. We calculated an expression value that corresponded to the group result for each participant. These expression values were submitted to 2 different classification algorithms: Fisher linear discriminant analysis and κ -nearest neighbor analysis. This classification procedure was cross-validated using the leave-one-out method.

Section of Sexual Medicine, Medical School, Christian Albrechts University of Kiel, Kiel, Germany.

We recruited 24 participants with pedophilia who were sexually attracted to either prepubescent girls (n = 11) or prepubescent boys (n = 13) and 32 healthy male controls who were sexually attracted to either adult women (n = 18) or adult men (n = 14). Sensitivity and specificity scores of the 2 classification algorithms.

The highest classification accuracy was achieved by Fisher linear discriminant analysis, which showed a mean accuracy of 95% (100% specificity, 88% sensitivity). Functional brain response patterns to sexual stimuli contain sufficient information to identify pedophiles with high accuracy. The automatic classification of these patterns is a promising objective tool to clinically diagnose pedophilia.

El autor: Section of Sexual Medicine, Christian Albrechts University, Kiel, Germany

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